Fatty Acid Oxidation- Step 1 in Fat Loss!

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This is How Your Body Uses Fat – Fun Analogy

Fatty Acid Oxidation- Step 1 in Fat Loss! – Thomas DeLauer

Awesome Analogy Brought in Part by Nicholas Norwitz – Ketone PhD Researcher and Harvard Med Student. Couldn’t create some of this epic content without my amazing team!

Fat Catabolism:

Fat is stored in fat cells called adipocytes. When energy is needed, fat is released from adipocytes into the bloodstream and travels to the cells that need it, such as a skeletal muscle cell. Once inside said skeletal muscle cell, the fatty acid is transported across the mitochondrial membrane into the inner mitochondrial matrix. Here it undergoes β-oxidation.

β-oxidation is a cyclical process in which 2-carbon acetyl-CoA molecules are progressively chopped off the end of a fatty acid chain until the entire fatty acid chain has been decomposed into acetyl-CoA. Each cycle of β-oxidation liberates one acetyl-CoA and two electron carriers (NADH and FADH2).

Acetyl-CoA then goes into the central metabolic pathway called the Kreb’s cycle to be fully oxidized/converted into CO2 and, in the process, generates more NADH and FADH2 (i.e. proteins, carbs, and ketones are all also converted into acetyl-CoA to go into the Kreb’s cycle). In the end, NADH and FADH2 provide the electrons to produce ATP via the electron transport chain.

Fat Burning:

A colloquialism (non-scientific term) used to refer to the conversation of fat tissue into energy.

Fat Oxidation:

Also known as β-oxidation (or β-oxidation plus the Kreb’s cycle), this scientific term refers to the biochemical processes that happen within mitochondria in which longer fatty acid chains are broken down to create energy.

Relationship between “Fat Burning” and “Fat Oxidation”:

It’s fair to say that “fat burning” refers to the whole process of fat in fat tissue being turned into energy, whereas “fat oxidation” refers either directly to (i) β-oxidation or to (ii) β-oxidation plus the oxidation of acetyl-CoA into CO2 (your choice). (i) is specific to fat. (ii) is more accurate, but confuses the issue slightly because all macronutrients are converted into acetyl-CoA. In brief, “fat oxidation” is a component of “fat burning,” the latter of which I also take to include the liberation of fat from adipocytes and its transport to other cells.

The “Log” Analogy!
Fat Cells: The Forest
Fatty Acid: Chopped-Down Tree/Long Logs
Muscle Cell Mitochondria: Campsite
β-oxidation: Axe
Acetyl-CoA: Firewood
Kreb’s cycle: Fire

Your fat cells are like a forest. To access the fire fuel, you first need to chop down the tree and transport the long wooden logs (fatty acids) to your campsite where you want to light the fire. Once at your campsite (muscle cell mitochondria), you can take your axe (β-oxidation) and chop up the long wooden logs (fatty acids) into smaller bits of firewood (Acetyl-CoA), which can then go on the fire (Kreb’s cycle).

The “Log” Analogy, (adapted to include ketones)!
β-oxidation Ketogenesis: Axe/lumberjack
Acetyl-CoA Ketones: Firewood
Brain: The Fireplace
Blood-brain barrier: The Front Door of Your House

Now imagine you want to light a fire in the fireplace in your house (your brain). You can’t very well take a whole chopped-down tree or long logs and move them through your front door (blood-brain barrier). Instead, you first need to chop up and process the long logs (fatty acids) into smaller bits of firewood and then transport those into your house. This chopping up and processing happens by the axe/lumberjack in your liver (ketogenesis), the smaller bits of brain-accessible firewood being ketones!

Circadian Rhythm

Beta Oxidation pathways follow a circadian rhythm. Study from PLOS One found that “mitochondrial fatty acid β-oxidation enzymes, i.e. carnitine palmitoyltransferase-1α (Cpt-1α) and medium chain acyl-CoA dehydrogenase (Acadm) to display daily rhythms with peak values during daytime.” And that they decline as the day goes on. So to maximize beta oxidation, cardio should be done earlier in the day


How To Eat Well On Your Fast Weight Reduction Diet

Foods abundant in fiber are an excellent source of carbs. Harvard scientists computed that changing a provided number of calories from polyunsaturated fat. Iron is an entrance to enhance the functioning of your red blood cells.

Fatty Acid Oxidation- Step 1 in Fat Loss!

The Very Best Weight Reduction Diet Guide For All Vegetarians

So the very first action the majority of people fall under is cutting back on your food intake. Yes you will lose some weight however this is not the very best way to do it. These foods consist of the nutrients required for your body.

If you’re pregnant, you’re most likely find yourself taken in with your brand-new baby’s needs. Possibly you currently understand about omega 3 and pregnancy, perhaps not. However you know your dietary needs are various now that your body is providing sustenance for your child.

To start, let’s return to a little bit of biology here. Do not fret weight loss nutrients this won’t be an uninteresting lesson like in school. It will apply some easy understanding about our bodies so we can see how juicers work.

These are the whole trees that still need to cut up into fire wood in order to fit into the stove. For the pigeons they are the legumes and grains such as corn, peas, barley and wheat. They belong to the starch group. There is likewise a cellulose group. This raw cellulose helps in the food digestion of various types of carbohydrates. It is simpler to cut up some grains then others.

For the very first four months, children get all the nutrients they need through their mom’s milk. There is likewise a supplement that is utilized in America that offers the baby all the nutrients it needs. After four months, moms start providing strong foods like cereals to their child, although all the required nutrient requirements are pleased by the breast milk. Moms and dads offer cereal to their child, which is abundant in iron as that would prevent any kind of allergies for the baby. After the cereal part is over, some vegetables and fruits are likewise added to the baby’s diet plan to satisfy all the other nutrient requirements. Whenever brand-new food is added, make sure that it is performed in a progressive and sluggish pace.

It depends on the design of the strategy, naturally, however they can be quite harmful to you. Much of these strategies are high in things that are bad for you, like hydrogenated fat and red meat. This would increase the danger for cardiovascular disease, and even some types of cancer.

They are discovered in bread, pasta, potatoes, rice, starchy vegetables, oatmeal, and dry beans and are the basis of a healthful diet plan. Starches are better than the easy sugars for numerous reasons.

Further, duplicated reheating in case of meat items is only going to make the dish feel unappetizing and bland. If you make usage of sluggish cookers, avoiding such issues will be extremely easy.

Juice fasting is likewise one way to detoxify and at the same time drop weight. It is constantly essential to speak with an expert prior to making your own bodybuilding meal strategy.

Fatty Acid Oxidation- Step 1 in Fat Loss! anti aging.

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