Do Vitamins Break a Fast? Supplements and Intermittent Fasting

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Do Vitamins Break a Fast? Supplements and Intermittent Fasting

Study – Rejuvenation Research

To understand how fasting might make cells stronger, researchers recruited 24 people and asked them to practice an intermittent fasting diet for two three-week periods

The study was designed as a 10-week double-crossover trial, consisting of two 3-week treatment periods – IF and IF with antioxidant supplementation

Each 3-week treatment period was preceded by a 1-week pre-conditioning period used to establish baseline caloric intake and to acclimate the participants to study-provided food.

During the first fasting period, participants ate a specially calibrated diet and during the second three week period, they ate that diet and took oral supplements of Vitamin C and Vitamin E

Because researchers just wanted to focus on how intermittent fasting affected cells, and not weight loss, participants ate 175% of their normal daily calorie intake on feasting days, and 25% of their normal daily intake on fasting days to prevent weight loss

They ate typical American food – things like pasta, chicken, sandwiches and desserts like ice cream, and took samples of blood before they started and just after they ended the diet so they could compare levels of byproducts of oxidative stress and markers of strong cell functioning

During the first three week period researchers attempted to see if fasting would increase oxidative stress (free radicals) in each person’s cells and to see if this stress actually led to stronger, more resilient cells

Looked to see if taking antioxidants in the second fasting period would block the free radicals caused by the fasting, preventing the cells from becoming more resilient

In other words, they wanted to know if Vitamin C and E would shelter the cells to the point that they wouldn’t be ready to stand up for themselves later on

Results

Found that in response to fasting every other day, the cells made more copies of a gene called SIRT3, which is part of a pathway that works to prevent free radical production and improve cellular repair processes

Specifically, there was a 2.7% increase in SIRT3 expression due to the IF diet, but no change in expression of other genes or oxidative stress markers analyzed

Also found a significant decrease in levels of circulating insulin, a sign that the participants bodies were more responsive to this hormone

One surprising finding is that when participants took daily oral supplements of Vitamin C and E, the benefits from fasting disappeared

It seems that because the cells were relatively sheltered from experiencing any oxidative stress that may have been caused by fasting every other day, they didn’t respond by increasing their natural defenses and improving their sensitivity to insulin and other stress signals

This suggests that low levels of environmental stress from things like fasting are actually good for our bodies, and that antioxidant supplements, while potentially good at certain times, might actually prevent our normal healthy cellular responses in other situations

Antioxidants & Autophagy

In turns out that some level of ROS production is required for the normal regulation of autophagy as well

A team of researchers at the University of Cambridge explored the relationship between autophagy and the production or reactive oxidative species

They found that it is possible to induce autophagy without increasing toxic ROS and that some antioxidants reduce autophagy

They looked at two types of non-HD cells (HeLa and COS-7 renal cells), adding rapamycin, an antibiotic, and trehalose, a sugar, both of which have been shown to induce autophagy

Each increased autophagy but neither increased ROS.
Next they looked at the effect of various antioxidants on autophagy in the COS-7 renal cells.

Autophagy was measured by levels of LC3-II, a marker for autophagosome formation and autophagosome-lysosome fusion

They looked at N-acetyl-cysteine (NAC), cystamine (in the pipeline as a potential HD treatment), and glutathione

All three impaired the induction of autophagy by trehalose in a dose dependent manner – they also looked at the effect of NAC and cystamine on rapamycin induced autophagy and on basal (normal, not induced levels of) autophagy and got similar results.

Also found that vitamin E impaired autophagy as well

Resources

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Herbal Nutrition For Your Good Health

For a nutrition plan go work, a plan you can stick with, you want to be able to enjoy the food your making. Get professional help in order to create your own weight loss plan. This goal lacks a purposeful reason for your actions.

Being A Vegetarian Doesn’t Mean Lacking Nutrition

They base their meal selections on nutritional value, including protein and calorie restriction goals. For most people that is going to work out to eating every four to six hours. Preventive healthcare is a far better alternative.

Nutrition…..When first starting out with a program such as P90x, Insanity, Turbo Fire or any other top sellers at Beachbody, the one thing that people always seem to struggle with is nutrition. Nutrition is the key to getting absolutely GREAT results. One thing that the people who got the best results from these programs have in common is that they had their nutrition locked down and they NEVER had a cheat meal during their 60 or 90 day challenge.

Simply assuming that your food choices measure up to your standards of nutrition is a frequent mistake. Bread that is advertised to be seven-grain may not actually contain whole grain at all. Giving the labels a closer look is the best way to be sure that what you are eating is healthy, because advertisements often exaggerate or omit information.

You know the saying, “What gets measured gets done.” Well it’s the same with your diet or weight loss program. If you don’t objectively and periodically measure your progress, you’re setting yourself up for major disappointment at the end of your diet or weight loss program. It is better if you know upfront and early on if you’re falling behind so that you can make the necessary adjustments and reap the desired goal/result.

So what is bad for us and what constitutes an unhealthy healthy diet? To begin with, all that pre-prepared food from the freezers of the supermarket should not be gracing your fridge. Ready meals and most frozen food is jam packed with salt, sugar and fat. Takeaways and fast food chains all sell food that is filled with unhealthy ingredients and is laden with salt and sugar which is what makes it taste so good. Sweets and snacks such as chocolate, crisps, cakes and biscuits are certainly no good in large amounts. All contain high levels of salt, sugar and fat which will lead to many health problems. Of course eating these foods once in a while is fine but consuming them every day is a recipe for weight gain and health issues.

Experts say, the most vital element is adequate nutrition. Crash diets – extremely low calorie or carbohydrate intake – have been associated with flat, dry, brittle, or thinning hair. What’s more, these diets aren’t truly healthy since they take out essential nutrients the body needs or have you drastically scale back on them. What makes you think the same diets will be great for your hair?

Take away the carbs – carbs will not only affect your skin care but can also affect you weight. Nothing is worse than being fat and having a bad skin condition. Cut away the carbs. Instead, eat healthy foods like whole-grain. Whole grain provides antioxidants that will help you with skin aging and will definitely delay the signs of skin aging and will give you a more youthful look and glow even in your 50s.

It is evident that nature has a delicate balance and it is up to humans to maintain that balance in order to have a healthy life. Without a healthy life a person can develop many diseases that will not only decrease the life expectancy but will also make life painful and tough due to many diseases and conditions. Thus, it is beneficial to have a healthy body that is in the best shape.

Your teeth and bones will need calcium to be healthy. Just follow the 5 a day concept whether you want to lose weight or not and live a healthy lifestyle. Choosing to eat right is a big step for some who are used to a rather unhealthy lifestyle.

Nutrition, Health, and FitnessDo Vitamins Break a Fast? Supplements and Intermittent Fasting.

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